SportsJaw
LeaderboardToday's GamesBest BetsLive OddsMake Picks
Login / Sign In
Today's GamesLatest PredictionsToday’s Best BetsLive OddsTeam PredictionsHead-to-Head MatchupsSJ CoinsAbout SportsJawContact UsLogin / Sign In
HomeMatchupsMake PicksLeaders
SportsJaw

The social platform for sports bettors.

Explore SportsJaw

  • Today’s Picks
  • Predictions
  • Best Bets
  • Leaderboard
  • Make Picks
  • Live Odds
  • Consensus Picks
  • Team Predictions
  • Head-to-Head
  • Game Briefing

Picks by Sport

  • NFL Picks
  • NCAAF Picks
  • NBA Picks
  • NCAAB Picks
  • MLB Picks
  • NHL Picks

About SportsJaw

  • How It Works
  • SJ Coins
  • Terms
  • Privacy
  • Contact Us

21+. Gambling problem? Call 1-800-GAMBLER. Picks are opinions, not guarantees. Past results do not predict future outcomes.

© 2026 SportsJaw. For entertainment purposes only. SportsJaw does not accept or place wagers.

  1. Home
  2. MLB Picks
  3. St. Louis Cardinals vs Baltimore Orioles
Mon 3:05 PM ET
St. Louis Cardinals logo
St. Louis
Cardinals2
E. FEDDE RHP
versus
Baltimore Orioles logo
Baltimore
Orioles5
C. Morton RHP
Final
Team123456789T
St. Louis Cardinals0000200002
Baltimore Orioles1013000

St. Louis Cardinals vs Baltimore Orioles Betting Picks & Predictions

Game time: May 26, 2025 at 3:05 PM ET

Venue: Oriole Park at Camden Yards — Baltimore, Maryland

Article updated May 26, 2:14 PM EDT

Published by SportsJaw Editorial Team

In this content, we preview the opening game of an interleague series between the St. Louis Cardinals and Baltimore Orioles. Both teams are looking to build momentum as they

Game outlook

In this content, we preview the opening game of an interleague series between the St. Louis Cardinals and Baltimore Orioles. Both teams are looking to build momentum as they face off in Charm City for a three-game set starting on Monday afternoon. The Cardinals come into this game after sweeping the Arizona Diamondbacks, while the Orioles split a four-game series in Boston. St. Louis has dominated recent matchups between the two teams, winning the last five meetings. The starting pitchers are Erick Fedde for the Cardinals and Charlie Morton for the Orioles. Baltimore is the favorite in this game, opening at -107, but the current line has St. Louis at -112 according to MLB cappers.

Betting Odds

Moneyline: Cardinals -112 | Orioles +100

Spread: Cardinals -1.5 (+130) | Orioles +1.5 (-155)

Total: Over/Under 9 (-110)

Based on the moneyline, the implied probability that Baltimore will win straight-up is 50%.

St. Louis Cardinals

St. Louis Cardinals swept Arizona at home with a one-run victory on Sunday, extending their winning streak to three games. The team's record stands at 30-23, placing them second in the NL Central, two games behind the Cubs. Brendan Donovan and Jordan Walker led the offense with multiple hits while Masyn Wynn hit his sixth home run of the season. Pitcher Sonny Gray threw six strong innings, but did not get the decision. John King and Phil Maton contributed to the bullpen's success, with Maton earning his second save of the year. Erick Fedde will start for the Cardinals in the upcoming game, boasting a 3-3 record and a 3.77 ERA this season. St. Louis ranks 8th in offense and 13th in defense in the league, with an average of 4.81 runs scored per game and 4.00 runs allowed per game.

0
—
5
MLB · St. Louis Cardinals at Baltimore Orioles

Your Picks on Cardinals vs Orioles

Picks closed
Runline
Moneyline
Total

21+. Gambling problem? Call 1-800-GAMBLER. Picks are opinions, not guarantees. Past results do not predict future outcomes.

Baltimore Orioles Analysis

Baltimore Orioles won the final two games of their series against the Red Sox, improving their record to 18-34 and moving out of the basement of the AL East. Ryan O'Hearn led the team with three runs and an RBI, while Dean Kremer earned the win with 5.1 scoreless innings. Charlie Morton will start the next game for the Orioles, looking to improve on his 0-7 record and 7.68 ERA this season. The Orioles have a power ranking of 29 and are struggling offensively, ranking 25th in the league. St. Louis has lost their last three matchups against Baltimore.

Baltimore team secures victories but concerns linger over Morton's performance; Cardinals face challenge on the road

The Baltimore team has secured two consecutive victories; however, there are concerns regarding Morton's performance this season, with his ERA improving to 7.68 from a concerning 10 on April 26th. Despite this improvement, Morton still has room for growth to be considered a competitive player currently. The Cardinals recently achieved a sweep against Arizona at home but face a challenge as they embark on an away game, where their record is 77-85 this season. Conversely, Baltimore struggles with an 8-15 home record, displaying a stark contrast to their successful seasons in 2023 and 2022. While Fedde's performance has been inconsistent, he has been effective in keeping the Cardinals competitive. Based on their recent successes, it is predicted that the Cardinals will secure a victory in this upcoming game.

SportsJawGame Predictions
Predicted score

Unavailable for this preview

Projected winnerUnavailableConfidencelow
Pick on the Spread

Published pick: Unavailable

Pick on the Total

Published pick: Unavailable

#StLouisCardinals#BaltimoreOrioles

Share this preview

Facebook X Reddit Email
SportsJaw logo
Written by

SportsJaw Editorial Team

SportsJaw published this archived preview from its original game-day article. Its prediction and quoted lines are preserved as written.

About our editorial process

SportsJaw Cardinals vs Orioles archived game preview contains historical odds and availability that may no longer be current. View history of past Cardinals vs Orioles matchups or learn how our predictions work.

Current matchup data

Lines, trends and availability

Line movement since open

  • Moneyline · St. Louis Cardinals-107 → -113Moved
  • Moneyline · Baltimore Orioles-107 → +101Moved
  • Spread · St. Louis Cardinals-1.25 (+128) → -1 (+135)Moved
  • Spread · Baltimore Orioles+1.25 (-151) → +1 (-160)Moved
  • Total · Over9.5 (-110) → 9 (-110)Moved
  • Total · Under9.5 (-110) → 9 (-110)Moved

ATS and O/U trends

St. Louis Cardinals
77-85 matchup record · 6-4-0 ATS · 5-4-1 O/U
Last 10 completed games on file
Baltimore Orioles
76-81 matchup record · 4-5-1 ATS · 6-4-0 O/U
Last 10 completed games on file

Injuries and availability

From the published research (2025-05-26T18:14:12.298Z). Availability may have changed; review the cited sources.

No verified injury or availability note was included in the published matchup research.

Recent head-to-head

No completed head-to-head result is available in the current history window.

Final result

Matchup pick recap

Baltimore Orioles defeated St. Louis Cardinals 5-2

Baltimore Orioles defeated St. Louis Cardinals 5-2 on May 26, 2025, a 3-run decision in the series. Baltimore Orioles' strongest period was the 4th inning, when it outscored its opponent 3-0. Against SportsJaw's recorded St. Louis Cardinals -1 (+135) spread, Baltimore Orioles covered, while the 7 combined runs finished under the recorded total of 9.

SportsJaw editorial picks

  • Projected winnerNo published selectionUnavailable

Tipster picks

  • CoolioMoneyline · St. Louis Cardinals -112Loss
  • CoolioTotal · Under 9 (-110)Win
  • OddssharkMoneyline · St. Louis Cardinals -112Loss