| Score | Moneyline | Spread | Game total | |
|---|---|---|---|---|
| Nebraska CornhuskersNEBR | 10 | +230 L | +7 (-110) L | O 45.5 (-110) W U 45.5 (-110) L |
| Penn St. Nittany LionsPENNST | 37 | -280 W | -7 (-110) W |
Penn St. Nittany Lions defeated Nebraska Cornhuskers 37-10
Penn St. Nittany Lions defeated Nebraska Cornhuskers 37-10 on November 22, 2025, a 27-point decision in the series. Penn St. Nittany Lions' strongest period was the 2nd quarter, when it outscored its opponent 16-3. Against SportsJaw's recorded Nebraska Cornhuskers +7 (-110) spread, Penn St. Nittany Lions covered, while the 47 combined points finished over the recorded total of 45.5.
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