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NCAAF MatchupsSat 3:30 PM ET
SMU
Mustangs
9-4
VS
Louisville
Cardinals
9-4
Game preview ↓
NCAAF · SMU at LOUISV

Your Picks on SMU vs Louisville

Picks close 15 minutes before game time (ET)
Spread
Moneyline
Total

SMU Mustangs vs Louisville Cardinals Predictions

Game date: September 19, 2026

By SportsJaw Editorial Team

SMU Mustangs at Louisville Cardinals

Game outlook

The current spread lists SMU Mustangs at +1.5 (-110) and Louisville Cardinals at -1.5 (-110). These are market lines, not a SportsJaw recommendation.

The total is 57.5 (-110) for the over and 57.5 (-110) for the under. A total pick concerns the teams’ combined score, independently of which team wins.

Opening vs current

SMU: opening spread +1.5 (-110); current spread +1.5 (-110). LOUISV: opening spread -1.5 (-110); current spread -1.5 (-110).

Opening over: 56.5 (-110). Current over: 57.5 (-110). Line changes alone do not establish an injury, lineup change, or betting advantage.

Moneyline

SMU Mustangs: -113. Louisville Cardinals: -118. Moneyline picks concern the outright winner rather than the winning margin.

Analysis status

A full SportsJaw game analysis has not been published for this matchup. Verified matchup factors, injury news, a projected score, and a recommended pick will appear only when supported by published analysis. The values here come directly from the current SportsJaw event record.

Current spreadSMU +1.5 (-110)LOUISV -1.5 (-110)
MoneylineSMU -113LOUISV -118
Total points57.5 (-110)
Projected score

No published projected score or confidence rating is available for this matchup.

SportsJaw Mustangs vs Cardinals game preview includes current market data. Lines and player availability can change. Please confirm current information before wagering. How our predictions work