| Score | Moneyline | Spread | Game total | |
|---|---|---|---|---|
| Buffalo BillsBUF | 23 | -585 W | -10.5 (-110) L | O 41 (-110) W U 41 (-110) L |
| Cleveland BrownsCLE | 20 | +430 L | +10.5 (-110) W |
Buffalo Bills defeated Cleveland Browns 23-20
Buffalo Bills defeated Cleveland Browns 23-20 on December 21, 2025, a 3-point decision in the series. Buffalo Bills' strongest period was the 2nd quarter, when it outscored its opponent 13-3. Against SportsJaw's recorded Buffalo Bills -10.5 (-110) spread, Cleveland Browns covered, while the 43 combined points finished over the recorded total of 41.
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