Get NFL picks, expert predictions, odds and scores for September 27, 2026. Open any matchup for current lines, consensus picks and SportsJaw game analysis.
| Date & time | Matchup | Spread | Moneyline | Total | Predictions |
|---|---|---|---|---|---|
New York Jets24Detroit Lions31 | +7 (-113)-7 (-107) | +260-325 | O 50 (-110)U 50 (-110) | Predictions: New York Jets vs Detroit Lions prediction | |
Houston Texans17Indianapolis Colts19 | -1.5 (-110)+1.5 (-110) | -123+103 | O 42.5 (-108)U 42.5 (-110) | Predictions: Houston Texans vs Indianapolis Colts prediction | |
New England Patriots6Jacksonville Jaguars35 | +3 (-110)-3 (-108) | +135-155 | O 46.5 (-115)U 46.5 (-105) | Predictions: New England Patriots vs Jacksonville Jaguars prediction | |
Carolina Panthers18Cleveland Browns21 | -2 (-110)+2 (-110) | -130+110 | O 41.5 (-110)U 41.5 (-110) | Predictions: Carolina Panthers vs Cleveland Browns prediction | |
Los Angeles Chargers16Buffalo Bills24 | +7 (-110)-7 (-110) | +274-340 | O 50.5 (-110)U 50.5 (-110) | Predictions: Los Angeles Chargers vs Buffalo Bills prediction | |
Kansas City Chiefs24Miami Dolphins10 | -10 (-105)+10 (-115) | -620+458 | O 45 (-110)U 45 (-110) | Predictions: Kansas City Chiefs vs Miami Dolphins prediction | |
Cincinnati Bengals27Pittsburgh Steelers30 | -3 (-112)+3 (-108) | -165+140 | O 42.5 (-108)U 42.5 (-113) | Predictions: Cincinnati Bengals vs Pittsburgh Steelers prediction | |
Tennessee Titans7New York Giants12 | +2.5 (-110)-2.5 (-110) | +115-135 | O 37.5 (-110)U 37.5 (-110) | Predictions: Tennessee Titans vs New York Giants prediction | |
Seattle Seahawks31Washington Commanders33 | -8.5 (-105)+8.5 (-115) | -400+315 | O 40.5 (-105)U 40.5 (-115) | Predictions: Seattle Seahawks vs Washington Commanders prediction | |
Arizona Cardinals30San Francisco 49ers36 | +7.5 (-110)-7.5 (-110) | +303-380 | O 48.5 (-110)U 48.5 (-108) | Predictions: Arizona Cardinals vs San Francisco 49ers prediction | |
Minnesota Vikings23Tampa Bay Buccaneers16 | -1.5 (+100)+1.5 (-120) | -110-110 | O 42.5 (-110)U 42.5 (-110) | Predictions: Minnesota Vikings vs Tampa Bay Buccaneers prediction | |
Las Vegas Raiders35New Orleans Saints27 | +3.5 (-110)-3.5 (-110) | +170-200 | O 44 (-110)U 44 (-110) | Predictions: Las Vegas Raiders vs New Orleans Saints prediction | |
Baltimore Ravens34Dallas Cowboys31 | -3.5 (+100)+3.5 (-120) | -171+150 | O 54 (-110)U 54 (-110) | Predictions: Baltimore Ravens vs Dallas Cowboys prediction | |
Los Angeles Rams26Denver Broncos30 | -1 (-108)+1 (-112) | -113-107 | O 44 (-110)U 44 (-110) | Predictions: Los Angeles Rams vs Denver Broncos prediction |
