Missouri Tigers vs Mississippi Rebels Predictions October 17, 2026
Mississippi is projected to beat Missouri, 31-27, on October 17, 2026. The Rebels’ red-zone scoring record and Trinidad Chambliss’ recent production give them a narrow edge against Missouri’s productive rushing attack. Missouri +6 (-110) offers the better betting opportunity because the Tigers have a credible route to a close finish. The official wager is that spread, with low confidence; the total is a Pass.
Missouri Tigers vs Mississippi Rebels prediction and best bet
Pick Mississippi to win and Missouri +6 (-110) to cover. The distinction rests on two different strengths: the Rebels have scored on every red-zone possession this season, while the Tigers bring a running back with consecutive 200-yard games. Mississippi gets the narrow winning edge; Missouri gets the spread recommendation.
The case for taking six points is that Missouri can sustain possessions through Jamal Roberts and make this a competitive fourth quarter. That is a forecast, not a guarantee that last week’s dominance carries over. Mississippi’s four takeaways against Vanderbilt are a substantial warning for anyone backing the underdog.
Odds, game time and how to watch
Game time: Saturday, October 17, 2026, at 3:30 p.m. EDT. This is a 2026 college football matchup with Missouri visiting Mississippi.
Venue: Vaught-Hemingway Stadium in Oxford, Mississippi.
Broadcast: SEC Network.
Records: Missouri is 5-1 overall and 2-1 in the SEC. Mississippi is 4-1 overall and 2-1 in conference play.
SportsJaw spread: Missouri +6 (-110); Mississippi -6 (-110).
SportsJaw total: Over 59.5 (-109); Under 59.5 (-111). Moneyline: Missouri +184; Mississippi -223.

