Iowa St. Cyclones vs Arizona Wildcats Predictions October 24, 2026
Arizona is the projected winner over Iowa State, 27-20, led by Noah Fifita and an offense that topped the Big 12 in passing yards per game through six games. Receiver injuries make the margin less certain than the winner. Neither Arizona -9.5 (-122) nor the 49.5 total offers a convincing wager here, so the official betting recommendation is Pass.
Iowa St. Cyclones vs Arizona Wildcats prediction and best bet
Arizona gets the pick for this October 24 college football matchup because its passing production offers the strongest reason to favor either team. Fifita’s accuracy and experience in Seth Doege’s offense support a Wildcats win. The forecast is Arizona 27, Iowa State 20, with low confidence.
Best bet: Pass. Arizona’s offensive numbers make it an appealing winner, but laying 9.5 points demands a stronger judgment about the matchup than those numbers alone can carry. With uncertainty around Arizona’s receivers and no comparable scoring or defensive profile for Iowa State, the favorite’s ability to pull away remains the central betting question.
Odds, game time and how to watch
Date and location: October 24, 2026, in Tucson, Arizona. The Wildcats host Iowa State for Homecoming during the 2026 season.
Arizona record and schedule: The Wildcats were 5-1 overall and 2-1 in Big 12 play through six games, according to Arizona Desert Swarm’s October 15 report. Their bye was October 17.
SportsJaw moneylines: Iowa State +330; Arizona -430.
SportsJaw spreads: Iowa State +9.5 (+100); Arizona -9.5 (-122).
SportsJaw total: 49.5, with Over 49.5 (-106) and Under 49.5 (-116).